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High Adherence to Dupilumab in Chronic Rhinosinusitis with Nasal Polyps: Insights from Real-World US Data

MedXY Editorial Team•Oct 4, 2025•news
biologicschronic rhinosinusitis with nasal polypsdupilumabtreatment adherence

Highlights

  • Real-world data from 3318 patients with CRSwNP showed persistence with dupilumab at 84.9% and 69.5% at 6 and 12 months, respectively.
  • Among patients who discontinued dupilumab, over 40% restarted treatment within 12 months, with a median reinitiation interval of 1.2 months.
  • Adherence rate was high, with 75.2% of patients achieving a medication possession ratio ≥ 0.8 during the 12-month follow-up.
  • Findings support sustained use and real-world effectiveness of dupilumab for CRSwNP and highlight the need for further study of persistence patterns in various patient subgroups.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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