Early Biologic Initiation in Severe Asthma: Enhancing Remission and Clinical Outcomes from Global Real-World Cohorts
Highlights
- Earlier initiation of biologics in severe asthma (SA) is associated with higher rates of clinical remission and improved asthma control.
- Delays in biologic treatment correlate with increased exacerbations, worsened lung function, and higher oral corticosteroid (OCS) burden.
- Real-world global data from CHRONICLE, ISAR, and OPCRD cohorts reinforce the importance of timely biologic accessibility and prescription policy reforms.
- Shifting asthma management from a ‘reserve’ to a ‘preserve’ approach could better maintain lung function and quality of life in patients with SA.
Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.