Background
Myopia has reached epidemic proportions globally, with particularly rapid progression in pediatric populations. Axial elongation remains the primary biomarker for myopia progression, correlating strongly with future vision-threatening complications. While Defocus Incorporated Multiple Segments (DIMS) lenses have demonstrated efficacy in clinical trials, this real-world study provides the first multicenter comparison of next-generation Diversified Segmental Defocus Optimization (DSDO) lenses against both DIMS technology and natural history controls.