Understanding Motivations and Barriers in Donation-Based HIV/STI Interventions: Insights from a Systematic Review

Highlight

• Donation-based interventions, such as secondary distribution of HIV self-tests and secondary syringe exchange, foster prosocial behaviors improving HIV/STI service reach.
• Givers are motivated by altruism and developing a prosocial identity, especially within close social networks, facilitating tailored and reciprocal health service distribution.
• Legal risks and potential for unsupervised clinical care pose barriers, particularly in secondary syringe exchange among people who inject drugs.
• Incorporating prosocial donation models could enhance HIV/STI program implementation globally, especially among marginalized populations.

Study Background