Comparative Diagnostic Accuracy of RIPASA and Modified Alvarado Scores in Acute Appendicitis: Insights from an Indian Tertiary Centre

Highlight

• The RIPASA score demonstrated higher sensitivity (94.6%) and better overall diagnostic discrimination (AUC 0.921) compared to the Modified Alvarado Score (MAS) in an Indian tertiary care setting.

• Modified Alvarado Score showed higher specificity (83.3%) than RIPASA (66.7%), implying fewer false positives but more missed cases.

• The study involved 62 patients undergoing appendectomy, with histopathological examination (HPE) as the diagnostic gold standard.

• RIPASA’s improved diagnostic performance suggests its utility in high-prevalence Asian populations where advanced imaging is not routinely accessible.

Study Background