– V116, a 21‑valent adult‑specific pneumococcal conjugate vaccine, elicited measurable opsonophagocytic activity (OPA) responses against all 21 vaccine serotypes in adults living with HIV.
– For the 13 serotypes shared with PCV15 and PPSV23, V116 responses at day 30 were generally similar to responses after PCV15 followed by PPSV23 at week 12; for the eight serotypes unique to V116, responses were higher than the comparator regimen.
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