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Age, Tumor Size, and Weight in Early-Stage Favorable Histology Wilms Tumor: Reevaluating Prognostic Indicators with COG Data

This pooled analysis from COG studies reveals that after accounting for tumor biology, age, tumor nephrectomy weight, and diameter are not independently predictive of outcomes in stage I/II favorable histology Wilms tumor, refining risk str

Oct 9, 2026Sign in to read

Hematology-Oncology

Lymph Node Assessment and Survival Outcomes in Favorable Histology Wilms Tumor: Insights from a Large COG Renal Tumor Study

This study evaluates how the number and positivity of lymph nodes affect survival outcomes in over 2,000 patients with stage I–III favorable histology Wilms tumor, underscoring the need for standardized lymph node sampling in surgical stagi

Sep 13, 2026Sign in to read

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Chromosome 1q Gain, Not Lung Nodule Burden, Best Predicts Outcomes in Stage IV Favorable‑Histology Wilms Tumor

In AREN0533, number and size of pulmonary metastases had limited prognostic value after standardized therapy; gain of chromosome 1q emerged as a stronger, independent predictor of event‑free and overall survival in children with favorable‑h

Dec 8, 2025