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Infectious Diseases

Strategic Release of Wolbachia-Infected Mosquitoes Reduces Dengue Risk by Over 70% in Urban Singapore

A large-scale cluster-randomized trial in Singapore demonstrates that releasing male Aedes aegypti mosquitoes infected with the wAlbB Wolbachia strain significantly suppresses wild-type populations and reduces the incidence of symptomatic d

Feb 22, 2026
Infectious Diseases

Efficacy and Challenges of Targeted Indoor Residual Spraying for Aedes-Borne Virus Prevention: Insights from a Cluster-Randomized Trial

This study evaluates targeted indoor residual spraying’s effectiveness against Aedes-borne diseases and highlights its limitations despite entomologic success.

Oct 25, 2025
Infectious Diseases

Mass Ivermectin Administration for Malaria Control: Translational Insights from Recent Cluster-Randomized Trials

Recent cluster-randomized trials in Kenya and Burkina Faso provide mixed but informative evidence on the efficacy and safety of mass ivermectin administration for malaria control, highlighting both its potential and limitations.

Jul 31, 2025

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