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vascular ageing

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Cardiology

METTL14 and LATS1/2 Define Divergent Endothelial Programs That Drive Vascular Ageing and Atherothrombosis — New Therapeutic Nodes in Cardio‑Vascular Senescence

Two complementary studies identify METTL14/TLR4 and LATS1/2–CD38–SUOX axes as key drivers of endothelial senescence phenotypes that promote arterial ageing, stiffness, fragile neovessels and atherothrombotic plaque formation, highlighting n

Dec 2, 2025
Cardiology

Ageing, Oral Microbiome, and Vascular Health: How Dietary Nitrate Unlocks Cardiovascular Benefits

Dietary nitrate supplementation alters age-related oral microbiome changes, enhancing nitric oxide bioavailability and reducing blood pressure in older adults, highlighting a novel mechanism for vascular health improvement.

Aug 30, 2025

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