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MedXY AI/MedXY News/Tag: vascular ageing
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METTL14 and LATS1/2 Define Divergent Endothelial Programs That Drive Vascular Ageing and Atherothrombosis — New Therapeutic Nodes in Cardio‑Vascular Senescence
CardiologyCD38vascular ageing

METTL14 and LATS1/2 Define Divergent Endothelial Programs That Drive Vascular Ageing and Atherothrombosis — New Therapeutic Nodes in Cardio‑Vascular Senescence

By MedXY|Dec 2, 2025

Two complementary studies identify METTL14/TLR4 and LATS1/2–CD38–SUOX axes as key drivers of endothelial senescence phenotypes that promote arterial ageing, stiffness, fragile neovessels and atherothrombotic plaque formation, highlighting n

Ageing, Oral Microbiome, and Vascular Health: How Dietary Nitrate Unlocks Cardiovascular Benefits
Cardiology
dietary nitrate
Nitric Oxide

Ageing, Oral Microbiome, and Vascular Health: How Dietary Nitrate Unlocks Cardiovascular Benefits

By MedXY|Oct 5, 2025

Dietary nitrate supplementation alters age-related oral microbiome changes, enhancing nitric oxide bioavailability and reducing blood pressure in older adults, highlighting a novel mechanism for vascular health improvement.

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