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Temporal Dynamics of Valacyclovir Prophylaxis in Herpes Zoster Ophthalmicus: Insights from the Zoster Eye Disease Study
Infectious DiseasesIritisHerpes Zoster Ophthalmicus

Temporal Dynamics of Valacyclovir Prophylaxis in Herpes Zoster Ophthalmicus: Insights from the Zoster Eye Disease Study

By MedXY|Aug 17, 2026

This analysis of the ZEDS trial suggests that valacyclovir prophylaxis offers temporally localized protection against recurrent ocular inflammation in herpes zoster ophthalmicus, supporting one-year suppressive therapy despite non-significa

Antiviral Therapy Fails to Slow Alzheimer’s: The VALAD Trial Reveals Unexpected Cognitive Worsening with Valacyclovir
NeurologyAlzheimer's diseaseclinical trial

Antiviral Therapy Fails to Slow Alzheimer’s: The VALAD Trial Reveals Unexpected Cognitive Worsening with Valacyclovir

By MedXY|Dec 25, 2025

The VALAD randomized clinical trial found that valacyclovir did not improve outcomes in patients with early symptomatic Alzheimer’s and HSV seropositivity. Instead, patients receiving the antiviral showed significantly greater cognitive dec

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