Urolithin A

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Urolithin A in Elite Distance Runners: Improves Recovery and Perceived Effort but Not Race Performance in 4-Week Altitude Training

A randomized, placebo-controlled trial in highly trained male distance runners found 4 weeks of 1000 mg/day urolithin A reduced markers of muscle damage and perceived exertion and upregulated mitochondrial proteomic pathways, but did not pr

Nov 4, 2025

Clinical Updates

Urolithin A for Muscle Health: A 4‑Month Randomized Trial Shows Improved Lower‑Limb Strength, Endurance Signals, and Mitochondrial Biomarkers

In a randomized, double‑blind 4‑month trial of middle‑aged overweight adults, oral urolithin A improved hamstring strength (~10–12%), increased peak VO2 and 6‑minute walk distance (clinically meaningful at 33 m for 1,000 mg), altered mitoch

Aug 9, 2025

Clinical Updates

Urolithin A Supplementation Enhances Muscle Endurance and Reduces Inflammation in Resistance-Trained Male Athletes: Insights from an 8-Week Randomized Controlled Trial

Urolithin A supplementation improved muscle endurance and reduced inflammatory and oxidative stress markers in resistance-trained male athletes over eight weeks, without significant adverse effects.

Aug 9, 2025