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Pre-diagnostic Clonal Hematopoiesis Raises Risk of Second Cancers in Patients With Primary Cancer
Hematology-OncologyCHIPhematologic malignancy

Pre-diagnostic Clonal Hematopoiesis Raises Risk of Second Cancers in Patients With Primary Cancer

By MedXY|Jun 8, 2026

Patients with primary cancer who had pre-diagnostic CHIP faced a higher risk of second cancers, especially blood cancers. The findings suggest CHIP may help identify survivors who need closer long-term monitoring.

Earlier Menopause Linked to Accelerated Multimorbidity Progression: UK Biobank Multi-State Analysis Reveals Critical Windows for Preventive Intervention
newschronic diseaseMenopause

Earlier Menopause Linked to Accelerated Multimorbidity Progression: UK Biobank Multi-State Analysis Reveals Critical Windows for Preventive Intervention

By MedXY|Apr 6, 2026

A large UK Biobank cohort study of 121,017 postmenopausal women reveals that earlier menopause significantly increases risks of multimorbidity progression, with women experiencing premature menopause facing 32% higher risk of developing fir

Delirium as a Sentinel Event: New UK Biobank Data Links Acute Brain Failure to Decades of Multisystem Vulnerability
Internal Medicineclinical outcomesdelirium

Delirium as a Sentinel Event: New UK Biobank Data Links Acute Brain Failure to Decades of Multisystem Vulnerability

By MedXY|Feb 15, 2026

A large-scale matched cohort study from the UK Biobank identifies in-hospital delirium as a sentinel marker for long-term multisystem vulnerability. Associated with increased risks of sepsis, AKI, and falls, delirium signals a profound phys

Holistic Mediterranean Lifestyle Linked to 35 Percent Lower Risk of Incident Chronic Kidney Disease
Nephrologychronic kidney diseasePreventive Nephrology

Holistic Mediterranean Lifestyle Linked to 35 Percent Lower Risk of Incident Chronic Kidney Disease

By MedXY|Feb 4, 2026

A large-scale prospective study from the UK Biobank reveals that high adherence to a Mediterranean lifestyle, including diet, physical activity, and social habits, significantly reduces the risk of developing chronic kidney disease over an

Protecting Your Kidneys and the Planet: The Impact of the Planetary Health Diet on Chronic Kidney Disease
NephrologyChế độ ăn uống vì sức khỏe hành tinhchronic kidney disease

Protecting Your Kidneys and the Planet: The Impact of the Planetary Health Diet on Chronic Kidney Disease

By MedXY|Jan 11, 2026

A large-scale study using UK Biobank data reveals that adhering to a Planetary Health Diet significantly lowers the risk of chronic kidney disease, emphasizing the dual benefits of plant-forward, sustainable eating for both personal health

Beyond Body Mass Index: How Sex-Specific Fat Distribution Drives Cardiovascular Ageing
Cardiologymachine learningUK Biobank

Beyond Body Mass Index: How Sex-Specific Fat Distribution Drives Cardiovascular Ageing

By MedXY|Jan 3, 2026

A large-scale UK Biobank study reveals that while visceral and liver fat accelerate cardiovascular ageing in both sexes, subcutaneous and android fat specifically impact males, whereas gynoid fat may offer protective benefits.

Evaluating AHA PREVENT Equations and Lipoprotein(a) in Cardiovascular Risk Stratification: Integrative Insights from MESA and UK Biobank Cohorts
CardiologyASCVDcardiovascular risk

Evaluating AHA PREVENT Equations and Lipoprotein(a) in Cardiovascular Risk Stratification: Integrative Insights from MESA and UK Biobank Cohorts

By MedXY|Dec 3, 2025

This review synthesizes evidence on the performance of AHA PREVENT equations in individuals with elevated lipoprotein(a), emphasizing its independent risk association and potential to enhance personalized ASCVD risk prediction.

Higher Endogenous Testosterone Is Associated with Lower Risk of Knee Osteoarthritis in Women
newsknee osteoarthritistestosterone

Higher Endogenous Testosterone Is Associated with Lower Risk of Knee Osteoarthritis in Women

By MedXY|Nov 2, 2025

In a large UK Biobank cohort, higher circulating testosterone was associated with lower prevalent and incident knee osteoarthritis (KOA) in middle-aged and older women, while SHBG and estradiol showed no clear associations.

Planetary Health and Plant-Based Diets: Reducing Type 2 Diabetes Risk in UK Adults
Diabetes & EndocrinologyPlanetary Health Diettype 2 diabetes

Planetary Health and Plant-Based Diets: Reducing Type 2 Diabetes Risk in UK Adults

By MedXY|Oct 20, 2025

Higher adherence to the Planetary Health Diet Index, reflecting environmentally sustainable plant-based eating patterns, is strongly associated with reduced type 2 diabetes risk in UK Biobank participants, comparable or superior to other es

Insulin Resistance Indices as Predictors of Cardio-Renal-Metabolic Multimorbidity: Insights from the UK Biobank
Cardiologyinsulin resistanceRisk Prediction

Insulin Resistance Indices as Predictors of Cardio-Renal-Metabolic Multimorbidity: Insights from the UK Biobank

By MedXY|Oct 19, 2025

This study demonstrates that insulin resistance indices, particularly TyG-WC, TyG-WHtR, and METS-IR, robustly predict the risk and progression of cardio-renal-metabolic multimorbidity, with inflammation and kidney function mediating these a

Unveiling the Impact of Pre-Clinical Alzheimer’s Disease on Blood Pressure: Insights from UK Biobank Mendelian Randomisation Studies
Cardiologyblood pressureMendelian randomisation

Unveiling the Impact of Pre-Clinical Alzheimer’s Disease on Blood Pressure: Insights from UK Biobank Mendelian Randomisation Studies

By MedXY|Oct 4, 2025

This study presents compelling evidence that pre-clinical Alzheimer’s disease increases systolic blood pressure, using innovative Mendelian randomisation and parental dementia instruments in UK Biobank data. These findings highlight complex

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