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Atezolizumab Demonstrates Moderate Efficacy in TMB-High Solid Tumors: Insights from the TAPISTRY Phase II Trial

The Phase II TAPISTRY trial evaluates atezolizumab in patients with high tumor mutational burden (TMB ≥13 or ≥16 mut/Mb), showing an objective response rate of approximately 20-22% across various solid tumors with a manageable safety profil

Jan 13, 2026
Clinical Updates

Distinct Genomic Mutation Patterns in Early-Onset Colorectal Cancer: Implications for Clinical Stratification and Precision Medicine

A large international study reveals unique somatic mutation profiles and higher mutational burden in hypermutated early-onset colorectal cancer, highlighting the need for age-specific molecular diagnostics and management strategies.

Aug 2, 2025

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