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Mitomycin C applied via injection or sponge during trabeculectomy offers comparable intraocular pressure control and safety, with injection potentially yielding more favorable bleb morphology and fewer postoperative interventions.
The TAGS Study shows trabeculectomy slows visual field loss more effectively than medical treatment in advanced glaucoma, yet this did not translate into significant quality-of-life improvements over five years, highlighting limitations in
A double-blind randomized trial found that a single intraoperative intravitreal bevacizumab injection improved 3-year trabeculectomy survival and reduced postoperative medication needs versus placebo.
