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Impact of Conditioning Regimens on Pregnancy Outcomes in Female Survivors of Childhood and Adolescent Acute Leukemia: HSCT versus Conventional Chemotherapy
Hematology-Oncology妊娠成績total body irradiation

Impact of Conditioning Regimens on Pregnancy Outcomes in Female Survivors of Childhood and Adolescent Acute Leukemia: HSCT versus Conventional Chemotherapy

By MedXY|Sep 12, 2026

This multicenter study reveals that total-body irradiation (TBI) conditioning before hematopoietic stem cell transplantation severely compromises pregnancy outcomes compared to alkylating agents or conventional chemotherapy in female surviv

Reassessing Total Body Irradiation in Young Children with ALL: Long-Term Safety and Outcomes
Hematology-Oncology
pediatric ALL
total body irradiation

Reassessing Total Body Irradiation in Young Children with ALL: Long-Term Safety and Outcomes

By MedXY|Aug 25, 2026

A French longitudinal study finds no increased long-term complications or compromised quality of life in children under 4 years undergoing TBI-based HSCT for acute lymphoblastic leukemia, challenging prior age restrictions.

Comparing Total Body Irradiation and Chemotherapy Conditioning in Haploidentical Transplants for AML Patients in First Remission: Insights from the EBMT Registry
Hematology-OncologyChemotherapy ConditioningHaploidentical Transplantation

Comparing Total Body Irradiation and Chemotherapy Conditioning in Haploidentical Transplants for AML Patients in First Remission: Insights from the EBMT Registry

By MedXY|Aug 10, 2026

This study evaluates survival and relapse outcomes of total body irradiation versus chemotherapy conditioning regimens in haploidentical hematopoietic cell transplantation for adult AML patients in first remission, revealing no clear surviv

Fludarabine with Treosulfan vs. Total Body Irradiation as Conditioning in ALL Transplantation: A Comparative Retrospective Analysis
Hematology-OncologyAcute Lymphoblastic Leukemiaallogeneic stem cell transplantation

Fludarabine with Treosulfan vs. Total Body Irradiation as Conditioning in ALL Transplantation: A Comparative Retrospective Analysis

By MedXY|Jul 12, 2026

This retrospective matched-pair study compares fludarabine combined with treosulfan or total body irradiation as conditioning regimens before allogeneic stem cell transplantation in adult acute lymphoblastic leukemia, finding no significant

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