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Combinational Tocolysis in Preterm Labor: Translating Ex Vivo Synergism of Nifedipine, Indomethacin, and Aminophylline Into Clinically Safer Short-Term Uterine Relaxation

A new ex vivo human myometrium study suggests that lower-dose nifedipine-based combinations may produce synergistic tocolysis, supporting a translational path toward safer short-term suppression of preterm labor.

Jun 10, 2026
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Atosiban Did Not Improve Neonatal Outcomes for Threatened Preterm Birth at 30–34 Weeks: Results from the Multicentre APOSTEL 8 Trial

In the APOSTEL 8 randomized trial, intravenous atosiban did not reduce a composite of perinatal mortality and severe neonatal morbidity versus placebo for threatened preterm birth at 30+0–33+6 weeks.

Nov 11, 2025

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