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Imaging-Detected Extranodal Extension in p16-Positive Oropharyngeal Cancer: Insights from the RTOG 1016 Study

This analysis of RTOG 1016 validates the prognostic value of imaging-detected extranodal extension (iENE) in p16-positive oropharyngeal cancer, supporting its integration into the AJCC/UICC TNM9 staging system and its implications for patie

Aug 31, 2026
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Optimizing Prognosis: The New AJCC Version 9 Staging for Salivary Gland Carcinoma

The proposed AJCC/UICC Version 9 staging for salivary gland carcinoma shifts toward a unified, specific system using lymph node count and extranodal extension, significantly improving prognostic accuracy for both major and minor salivary gl

Feb 20, 2026
Oncology

Revising the TNM Classification for HPV-Associated Oropharyngeal Carcinoma: Improving Prognostic Stratification with Imaging-Detected Extranodal Extension

A new clinical TNM staging proposal incorporating imaging-detected extranodal extension (iENE) refines prognostic accuracy in HPV-positive oropharyngeal carcinoma, aiding risk stratification and future treatment strategies.

Oct 22, 2025

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