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Gastroenterology

Decoding Systemic Inflammation in Long COVID and Autoimmune Diseases: The Role of Intestinal Flagellin and the TLR5-IL-15-ARA Axis

This article explores how intestinal flagellin drives systemic inflammation via the TLR5-IL-15-ARA pathway in long COVID, rheumatoid arthritis, ankylosing spondylitis, and IBD, highlighting potential therapeutic targets and biomarkers.

Aug 22, 2026Sign in to read
Gastroenterology

Unraveling the Gut-Lung Axis: Intestinal Flagellin as a Driver of Multisystem Inflammation via the TLR5-IL-15-ARA Pathway

Flagellated gut bacteria activate TLR5 on neutrophils, triggering IL-15 release and macrophage arachidonic acid production, driving systemic inflammation in long COVID, rheumatoid arthritis, ankylosing spondylitis, and IBD.

Aug 21, 2026Sign in to read
Family Medicine & Nutrition

The Gut’s Sixth Sense: How Your Microbiome Quietly Controls Appetite

Recent research unveils a ‘neurobiotic sense’ in the gut that detects bacterial molecules and regulates feeding through the gut-brain axis, reshaping our understanding of appetite control.

Aug 31, 2025

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