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Detection of genomic alterations via Afirma Xpression Atlas in indeterminate thyroid nodules enhances malignancy risk stratification beyond Afirma GSC results, guiding surgical decision-making.
In a large single-center retrospective study, ACR TI-RADS implementation decreased follow-up thyroid ultrasound but did not reduce fine-needle aspiration, surgery, cancer yield, or overall costs.
Thyroid nodules larger than 4 cm often require surgery due to potential compression of surrounding tissues, but smaller nodules with signs of malignancy or symptoms may also need surgical intervention. This article explains the criteria in