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Unraveling Central Autonomic Network Disruptions Underlying Cardiorespiratory Dysfunction in Temporal Lobe Epilepsy
Cardiologytemporal lobe epilepsyCardiorespiratory Regulation

Unraveling Central Autonomic Network Disruptions Underlying Cardiorespiratory Dysfunction in Temporal Lobe Epilepsy

By MedXY|Sep 6, 2026

This study reveals that central autonomic network alterations in temporal lobe epilepsy patients contribute to interictal cardiorespiratory dysfunction, potentially increasing SUDEP risk, and highlights connectivity changes post-surgery imp

Impaired Sleep Homeostasis and Respiratory Instability: Identifying Novel Biomarkers for Sudden Unexpected Death in Epilepsy
NeurologyepilepsySUDEP
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Impaired Sleep Homeostasis and Respiratory Instability: Identifying Novel Biomarkers for Sudden Unexpected Death in Epilepsy

By MedXY|Dec 23, 2025

This case-control study identifies altered slow-wave activity progression and increased respiratory variability during NREM sleep as significant biomarkers for SUDEP risk, providing a potential framework for objective clinical screening and

Extratemporal epilepsy, obesity and male sex predict SUDEP risk in drug‑resistant focal epilepsy: clinical insights from the REPO2MSE prospective case‑control study
Neurologybiomarkersfocal epilepsy

Extratemporal epilepsy, obesity and male sex predict SUDEP risk in drug‑resistant focal epilepsy: clinical insights from the REPO2MSE prospective case‑control study

By MedXY|Dec 1, 2025

A multicentre prospective nested case‑control analysis (REPO2MSE) identifies extratemporal seizure onset, BMI ≥30, male sex, and predominantly nocturnal seizures as independent SUDEP risk factors in drug‑resistant focal epilepsy; peri‑ictal

Decoding SUDEP: Key Risk Markers and the Role of Peri-Ictal Apnoea in Epilepsy Mortality
NeurologyepilepsySUDEP

Decoding SUDEP: Key Risk Markers and the Role of Peri-Ictal Apnoea in Epilepsy Mortality

By MedXY|Oct 10, 2025

A decade-long prospective study identifies living alone, convulsive seizure frequency, and peri-ictal apnoea as pivotal predictors for sudden unexpected death in epilepsy (SUDEP), highlighting the potential of cardiorespiratory monitoring i

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