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This study compares the effectiveness of inpatient rehabilitation facilities and skilled nursing facilities on functional recovery after acute stroke, showing inpatient care offers greater long-term home time.
The LAST-long trial investigated a community-based, individualized stroke intervention and found that age—but not frailty—significantly modifies its effectiveness, with older stroke survivors (≥80 years) experiencing less favorable outcomes
This feasibility RCT demonstrates that the HOPE4ABI digital intervention is acceptable and beneficial for improving mental, sexual wellbeing, and quality of life in stroke and brain injury survivors, warranting a definitive efficacy trial.
A feasibility RCT demonstrates that a telehealth-delivered behaviour change intervention, augmented with a physical activity monitor, can increase physical activity in post-stroke individuals, supporting future large-scale trials.
A randomized clinical trial demonstrates that blood flow restriction training, through BFR-walking or low-load resistance training, improves lower limb motor function and balance in stroke survivors beyond conventional rehabilitation.
A 2024 multicenter study in Amhara, Ethiopia found nearly 80% of stroke survivors experienced fall-related injuries, with older age, rural residency, and walking/turning activities as key risk factors.
Paired vagus nerve stimulation (VNS) combined with rehabilitation achieves significant and durable improvements in upper extremity function, participation, and quality of life up to two years after chronic ischemic stroke, highlighting its
A multicenter randomized controlled trial reveals that integrating action observation with virtual reality significantly improves paretic hand dexterity in stroke patients, with benefits persisting six months post-intervention, offering a s
A comprehensive review of a multicenter RCT (Morone et al., 2026) demonstrating that exoskeleton-based robot-assisted therapy significantly improves upper limb motor impairment and clinical outcomes in the early subacute phase of stroke rec
A pivotal randomized clinical trial reveals that targeted training of the ipsilesional arm in chronic stroke patients with severe hemiparesis significantly improves motor speed and hand function, with benefits sustained for six months.
A randomized clinical trial reveals that targeted training of the ipsilesional arm significantly improves motor performance in chronic stroke patients with severe contralesional impairment, offering a sustained pathway to enhance functional
A randomized trial demonstrates that a 50-fold smaller, closed-loop vagus nerve stimulation (CLV) system is safe and significantly improves upper limb function in chronic stroke patients, with functional gains doubling during extended home-
The Phase II HiWalk trial demonstrates that a 43-hour high-intensity walking booster program is safe and feasible for chronic stroke survivors, yielding significant walking speed improvements for individuals who have already completed their
The TaCAS long-term follow-up study reveals that a simple, conversation-based intervention can sustain improvements in physical health and independence for up to six years post-stroke, highlighting the lasting impact of patient-centered mot
The Walk ‘n Watch trial shows that a structured, progressive walking protocol significantly improves endurance in subacute stroke patients, providing a 43.6-meter advantage over usual care without increasing serious adverse events.
The LAST-long randomized trial found that an 18-month coordinator-led multimodal intervention did not significantly prevent functional decline or dependency in patients with mild stroke compared to standard care, highlighting challenges in
Evidence suggests combined aerobic and strength training post-stroke yields modest improvements in fitness and function but uncertain long-term benefits.
This article analyzes recent findings on sociodemographic and geographic disparities in community-based stroke rehabilitation from the COMPASS trial.
Moderate-quality evidence from 14 RCTs supports combined immersive and nonimmersive VR with mirror therapy to enhance upper extremity function and hand dexterity in stroke survivors, though clinical significance needs cautious interpretatio
The ESTREL trial demonstrates that levodopa added to standardized rehabilitation does not significantly improve motor recovery after acute stroke, challenging its adjunctive use for enhancing neuroplasticity in stroke rehabilitation.
