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steroid-sparing therapy

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Allergy & Immunology

Zetomipzomib Shows Promise in Difficult-to-Treat Autoimmune Hepatitis: Insights from the Phase 2a PORTOLA Study

The PORTOLA phase 2a trial evaluates zetomipzomib, a selective immunoproteasome inhibitor, demonstrating numerically improved biochemical remission and steroid-sparing effects in autoimmune hepatitis patients with inadequate response to sta

Sep 25, 2026
Internal Medicine

Higher Oral Corticosteroid Exposure in Chronic Rhinosinusitis With Nasal Polyps Is Linked to More Systemic Harm

A nationwide Korean nested case-control study found that longer annual duration and higher cumulative oral corticosteroid dose in chronic rhinosinusitis with nasal polyps were associated with increased systemic adverse events, supporting st

Jun 6, 2026

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