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Hypoxia-Induced BACH1 Elevation Drives Pulmonary Hypertension via Activation of TGFBR2/SMAD Signaling
CardiologyBACH1Huyết Áp Phổi

Hypoxia-Induced BACH1 Elevation Drives Pulmonary Hypertension via Activation of TGFBR2/SMAD Signaling

By MedXY|Jul 15, 2026

BACH1 stabilization under hypoxia promotes pulmonary hypertension by enhancing TGFBR2/SMAD pathway activity in pulmonary artery smooth muscle cells, suggesting BACH1 as a promising therapeutic target for PH.

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