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Respiratory Syncytial Virus Vaccine Effectiveness in Medicare Beneficiaries Residing in Nursing Homes: A Comprehensive Review
Clinical UpdatesRSV vaccinenursing homes

Respiratory Syncytial Virus Vaccine Effectiveness in Medicare Beneficiaries Residing in Nursing Homes: A Comprehensive Review

By MedXY|Sep 11, 2026

This review synthesizes emerging evidence demonstrating robust effectiveness of RSV vaccination in reducing hospitalization, death, and severe outcomes among elderly nursing home residents during the vaccine’s inaugural season.

Evaluating the Safety of Prenatal RSVpreF Vaccination: Implications for Obstetric and Neonatal Outcomes
Infectious DiseasesRSV vaccine
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Pregnancy

Evaluating the Safety of Prenatal RSVpreF Vaccination: Implications for Obstetric and Neonatal Outcomes

By MedXY|Aug 18, 2026

A large-scale VSD study found that prenatal vaccination with bivalent prefusion F RSV vaccine is generally safe, showing no increased risk for preterm birth, stillbirth, or small-for-gestational-age births but a slight increase in hypertens

High Effectiveness and Rare Safety Risks: Real-World Meta-Analysis Validates RSV Vaccination for Older Adults
Infectious Diseasesgeriatricspublic health

High Effectiveness and Rare Safety Risks: Real-World Meta-Analysis Validates RSV Vaccination for Older Adults

By MedXY|Mar 4, 2026

A comprehensive meta-analysis of 121.8 million individuals confirms that RSV vaccines are approximately 75% effective against hospitalization and severe disease in older adults, despite low global uptake and a rare risk of Guillain-Barré sy

Durability and Decay: Evaluating Long-term RSV Vaccine Effectiveness in a Large Real-World Cohort of US Veterans
Clinical Updatesgeriatric medicineimmunocompromised

Durability and Decay: Evaluating Long-term RSV Vaccine Effectiveness in a Large Real-World Cohort of US Veterans

By MedXY|Jan 2, 2026

This review analyzes the long-term effectiveness of RSV vaccination among US Veterans, revealing significant protection against severe outcomes that wanes over two seasons, particularly in immunocompromised populations.

Bivalent RSV pre‑F Vaccine Dramatically Reduces RSV‑Associated Hospitalisations and Chronic‑Disease Exacerbations in Adults Aged 75–79 Years
Infectious Diseasesolder adultsRSV vaccine

Bivalent RSV pre‑F Vaccine Dramatically Reduces RSV‑Associated Hospitalisations and Chronic‑Disease Exacerbations in Adults Aged 75–79 Years

By MedXY|Nov 24, 2025

In a multicentre test‑negative study of 1006 adults aged 75–79 in England, a bivalent RSV pre‑F vaccine reduced RSV‑associated hospitalisation by 82% overall and protected against severe disease and exacerbations of chronic heart and lung d

RSV prefusion F bivalent vaccine protects older adults similarly whether or not they have atherosclerotic cardiovascular disease
Cardiologyatherosclerotic cardiovascular diseaseolder adults

RSV prefusion F bivalent vaccine protects older adults similarly whether or not they have atherosclerotic cardiovascular disease

By MedXY|Nov 11, 2025

In a prespecified secondary analysis of the DAN‑RSV randomized trial, the bivalent RSV prefusion F vaccine showed comparable effectiveness against RSV‑related respiratory hospitalizations in adults ≥60 years with and without pre‑existing at

Effectiveness and Safety of RSV Vaccination in US Adults Aged 60 Years or Older: A Comprehensive Evidence Synthesis
Clinical Updatesolder adultsRSV vaccine

Effectiveness and Safety of RSV Vaccination in US Adults Aged 60 Years or Older: A Comprehensive Evidence Synthesis

By MedXY|Oct 31, 2025

RSV vaccines demonstrate substantial effectiveness and acceptable safety profiles in adults aged ≥60, with diminished effectiveness in immunocompromised subgroups and a low, statistically significant increased risk of Guillain-Barré syndrom

Updated Evidence for Covid-19, RSV, and Influenza Vaccines in the 2025-2026 Season: A Comprehensive Review
Infectious DiseasesCOVID-19 vaccineinfluenza vaccine

Updated Evidence for Covid-19, RSV, and Influenza Vaccines in the 2025-2026 Season: A Comprehensive Review

By MedXY|Oct 31, 2025

A systematic review supports the continued safety and effectiveness of Covid-19, RSV, and influenza vaccines for the upcoming 2025-2026 season, highlighting detailed vaccine efficacy, safety profiles, and recommendations for at-risk populat

Three-Season Protection Against RSV in Older Adults: Insights from the AReSVi-006 Phase 3 Trial of the AS01E-Adjuvanted RSVPreF3 OA Vaccine
Infectious Diseasesolder adultsRSV vaccine

Three-Season Protection Against RSV in Older Adults: Insights from the AReSVi-006 Phase 3 Trial of the AS01E-Adjuvanted RSVPreF3 OA Vaccine

By MedXY|Oct 4, 2025

The AS01E-adjuvanted RSVPreF3 OA vaccine demonstrates robust efficacy against RSV-related lower respiratory tract disease over three seasons in adults aged 60+, with a favorable safety profile and promising immunogenicity findings.

Evaluating the Safety and Immunogenicity of the Adjuvanted RSVPreF3 Vaccine in High-Risk Transplant Recipients: A Critical Analysis of an Interventional Cohort Study
Infectious DiseasesimmunogenicityRSV vaccine

Evaluating the Safety and Immunogenicity of the Adjuvanted RSVPreF3 Vaccine in High-Risk Transplant Recipients: A Critical Analysis of an Interventional Cohort Study

By MedXY|Oct 6, 2025

This study assesses the safety and immune response of an adjuvanted RSVPreF3 vaccine in adult allogeneic hematopoietic cell and lung transplant recipients, highlighting modest antibody responses but robust CD4+ T-cell activation, supporting

Evaluating RSV Vaccine Effectiveness Against Hospitalization in US Adults Aged 60 and Older Over Two Seasons
Clinical Updateshospitalizationolder adults

Evaluating RSV Vaccine Effectiveness Against Hospitalization in US Adults Aged 60 and Older Over Two Seasons

By MedXY|Oct 6, 2025

A large multicenter study demonstrates that a single dose of RSV vaccine reduces hospitalization risk by 58% among adults aged 60+, with lower effectiveness in immunocompromised and cardiovascular patients.

Bivalent RSV Prefusion F Protein Vaccine: A Potential Strategy to Reduce Cardiovascular Hospitalizations in Older Adults
Cardiologycardiovascular diseaseelderly

Bivalent RSV Prefusion F Protein Vaccine: A Potential Strategy to Reduce Cardiovascular Hospitalizations in Older Adults

By MedXY|Jan 13, 2026

The DAN-RSV trial demonstrates that RSV vaccination significantly lowers all-cause cardiorespiratory hospitalizations among older adults, suggesting vaccines may reduce infection-triggered cardiovascular complications and benefit chronic di

Promising Immunogenicity and Safety of the Live-Attenuated Intranasal RSV Vaccine in Infants and Toddlers
Pediatricsimmunogenicityinfants

Promising Immunogenicity and Safety of the Live-Attenuated Intranasal RSV Vaccine in Infants and Toddlers

By MedXY|Oct 5, 2025

This phase I/II trial demonstrates that the live-attenuated intranasal RSV vaccine (RSVt) is immunogenic and well-tolerated in infants and toddlers, offering a potential new preventive option against RSV infection.

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