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RNA Splicing

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Hematology-Oncology

Targeting PRMT9 to Overcome Venetoclax Resistance in AML: A Paradigm Shift in Therapeutic Strategy

PRMT9-mediated arginine methylation drives venetoclax resistance in AML by altering RNA splicing and protein synthesis. Targeting PRMT9 restores venetoclax sensitivity, offering a promising approach to combat resistant AML.

Sep 13, 2026Sign in to read
Neurology

Genetic Breakthrough: How SNUPN Gene Variants Lead to Spinocerebellar Atrophy

Researchers have discovered that mutations in the SNUPN gene cause spinocerebellar atrophy by disrupting RNA splicing in Purkinje cells, expanding the understanding of neurodevelopmental disorders beyond muscular conditions.

Mar 6, 2026

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