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Evaluating Riociguat in Early Pulmonary Vascular Disease: Insights from the ESRA Phase IIa Trial
Cardiologyclinical trialpulmonary arterial hypertension

Evaluating Riociguat in Early Pulmonary Vascular Disease: Insights from the ESRA Phase IIa Trial

By MedXY|Jul 17, 2026

The ESRA trial demonstrates that riociguat is safe and effectively reduces pulmonary vascular resistance in early pulmonary vascular disease, though secondary benefits remain unproven in this early-stage, mostly connective tissue disease-as

Riociguat Continuation After Balloon Pulmonary Angioplasty Preserves Exercise Capacity in Inoperable CTEPH: Insights from the THERAPY-HYBRID-BPA Trial
General SurgeryBalloon pulmonary angioplastyexercise capacity

Riociguat Continuation After Balloon Pulmonary Angioplasty Preserves Exercise Capacity in Inoperable CTEPH: Insights from the THERAPY-HYBRID-BPA Trial

By MedXY|Oct 8, 2025

The THERAPY-HYBRID-BPA study demonstrates that continuing riociguat after balloon pulmonary angioplasty maintains exercise capacity in patients with inoperable chronic thromboembolic pulmonary hypertension without increasing adverse events.

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