restrictive transfusion

Restrictive versus Liberal Transfusion Thresholds in Very Low Birthweight Infants: Fewer Transfusions Without Harm to Survival or Early Neurodevelopment

A Cochrane meta-analysis of six RCTs (3,451 infants) finds restrictive hemoglobin thresholds reduce transfusion exposure modestly with no detectable effect on mortality or neurodevelopmental impairment at 18–26 months.