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Antifibrotic Repurposing: How Finerenone Could Rejuvenate the Ovarian Niche and Restore Fertility in POI

A breakthrough study in Science reveals that the antifibrotic drug finerenone restores fertility in premature ovarian insufficiency (POI) by reducing ovarian stromal fibrosis, enabling follicle development where hormone therapy previously f

Feb 7, 2026Sign in to read
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Does Size Matter? Re-evaluating Endometrial Thickness Thresholds in 30,000 Euploid Embryo Transfers

An international multicenter study confirms that endometrial thickness below 7 mm reduces live birth rates in most frozen embryo transfer protocols, though the impact is notably absent in natural cycles and overall predictive power remains

Dec 26, 2025
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Challenging the Compaction Paradigm: Why Endometrial Thinning May Not Predict Pregnancy Success in HRT-FET

A large-scale analysis of over 16,000 cases reveals that endometrial compaction following progesterone administration does not improve pregnancy outcomes in HRT-FET, and may even be associated with lower success rates in blastocyst transfer

Dec 26, 2025
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Rethinking Mosaicism: Why Reporting Putative Mosaic Embryos Fails to Improve IVF Outcomes

A large, double-blinded study reveals that reporting embryo mosaicism (ICN) during PGT-A provides no meaningful clinical predictive value for live birth rates, suggesting that current classification systems may unnecessarily limit embryo se

Dec 24, 2025
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Optimising Ovulation Timing in Intrauterine Insemination: Evidence Still Unclear

A Cochrane review finds no definitive evidence on the best method to synchronise insemination with ovulation in subfertile couples undergoing IUI.

Dec 18, 2025

Most read

  1. 01Intimate Health

    Five Benefits for Women Continuing Sexual Activity After Menopause

  2. 02Intimate Health

    Why Some Women Have a Strong Sex Drive—And Why Men Shouldn't Worry About It

  3. 03Nursing & care

    How often should a couple have sex?

  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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