Tag
Two large randomized trials reveal that testosterone therapy improves sexual function and mood without increasing cardiovascular risks in men with age-related low testosterone, but does not enhance vitality or physical function.
This article reviews the accelerated evidence generation for anticoagulation in noncritically ill COVID-19 patients, highlighting how coordinated trials and data sharing influenced clinical guidelines and patient outcomes during the pandemi
This systematic review evaluates lithium’s efficacy in reducing suicidal ideation, attempts, and completed suicide, highlighting methodological challenges and the likelihood of benefit despite lack of statistical significance in RCTs.
An umbrella review synthesizes evidence from 156 RCTs assessing probiotics’ effects on cognitive-related outcomes, showing moderate- to high-quality support for cognitive benefits but highlighting need for further trials on strains an
This systematic review and meta-analysis of randomized controlled trials finds no significant association between proton pump inhibitor use and increased risk of Clostridioides difficile infection, challenging earlier observational data and
This review evaluates the DASH diet’s impact on major cardiovascular outcomes, synthesizing evidence from RCTs and highlighting its benefits on blood pressure and lipid profiles amid gaps in long-term clinical outcome data.
Digital health interventions show modest but clinically meaningful reductions in waist circumference for overweight and obese adults, highlighting their potential as adjuncts in obesity care despite limited effects on weight and behavior.
