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Allogeneic Stem Cell Transplantation After 70: Japanese Registry Data Define Who May Benefit Most
Hematology-OncologyAllo-HSCThematologic malignancy

Allogeneic Stem Cell Transplantation After 70: Japanese Registry Data Define Who May Benefit Most

By MedXY|Jun 19, 2026

A Japanese registry study of 929 patients aged 70+ identified six predictors of worse survival after allo-HSCT and created a simple score that sharply stratified 2-year overall survival from 57.1% to 2.5%.

A New Frontier in Fabry Cardiomyopathy: Validating a T1-Inclusive Prognostic Score for Cardiovascular Risk
CardiologyCardiac Magnetic Resonanceprognostic score
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A New Frontier in Fabry Cardiomyopathy: Validating a T1-Inclusive Prognostic Score for Cardiovascular Risk

By MedXY|Jan 5, 2026

This article explores a novel 3-year prognostic score for Fabry Disease cardiomyopathy, integrating CMR-derived T1 values, LV mass, and LGE extent to predict adverse events, emphasizing the negative predictive value of normal T1 mapping.

SOFA-2 Recalibrated: Global Development and Validation of an Updated Organ Dysfunction Score in >3.3 Million ICU Admissions
Critical Carecritical careorgan dysfunction

SOFA-2 Recalibrated: Global Development and Validation of an Updated Organ Dysfunction Score in >3.3 Million ICU Admissions

By MedXY|Nov 8, 2025

SOFA-2 updates the 30-year-old SOFA score using data from >3.3 million ICU admissions across diverse settings. The revised tool modestly improves ICU mortality discrimination (AUROC 0.79 vs 0.77) and incorporates contemporary organ suppo

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