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The PRO-PLATINUM trial evaluates a novel 5-strain probiotic’s effect on gut and vaginal microbiome composition and clinical outcomes in ovarian cancer patients undergoing platinum chemotherapy, assessing safety, feasibility, and trans
A randomized clinical trial reveals that while Limosilactobacillus reuteri probiotics do not enhance local periodontal healing compared to standard therapy, they significantly improve systemic glycemic control (HbA1c) in patients with diabe
A 2025 Cochrane update finds probiotics may halve the relative risk of C. difficile-associated diarrhea in antibiotic-treated patients (ARR 1.6%, NNT 65) but evidence is low certainty and applicability varies with baseline risk.
An umbrella review synthesizes evidence from 156 RCTs assessing probiotics’ effects on cognitive-related outcomes, showing moderate- to high-quality support for cognitive benefits but highlighting need for further trials on strains an
This study evaluated the antidepressant effects of a Lactobacillus probiotic in overweight depressed patients with systemic low-grade inflammation, revealing no overall benefit but highlighting fecal formic acid as a potential biomarker for
A 3-month RCT demonstrates that multi-species probiotic supplementation improves vagal nerve function, gut microbiome composition, and sleep quality in patients with major depression, suggesting novel gut-brain axis interventions.
A 12-week trial in children with ASD demonstrates that a structured anti-inflammatory dietary protocol (NeuroGutPlus) exerts broader immunoregulatory effects than multi-strain probiotics, highlighting diet as a promising non-pharmacological
Probiotic pretreatment improves Helicobacter pylori eradication rates and reduces side effects, offering a promising adjunctive strategy to overcome treatment challenges and antibiotic resistance.
Akkermansia muciniphila supplementation improves metabolic outcomes in overweight/obese type 2 diabetes patients only when baseline gut levels are low, underscoring the need for personalized microbiota-guided interventions.
Explore how probiotics and prebiotics fortify gut health, boosting immune response and overall well-being.
A practical guide to selecting effective probiotic products, separating evidence from myths, and making informed choices for digestive and overall health.
Akkermansia is gaining popularity for its potential anti-inflammatory and anti-aging benefits, but its effects are still under scientific evaluation.
Emerging science reveals how your gut and brain communicate, shaping not only digestion but also emotions and mental health.