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Mapping ADHD Heterogeneity: A New Frontier in Neurobiological Biotyping through Morphometric Similarity Networks
Clinical UpdatesADHDNeuroimaging

Mapping ADHD Heterogeneity: A New Frontier in Neurobiological Biotyping through Morphometric Similarity Networks

By MedXY|Mar 2, 2026

This review explores a groundbreaking study using normative modeling and morphometric similarity networks to identify three distinct neurobiological biotypes of ADHD, providing a framework for precision psychiatry.

Decoding Antidepressant Response: Genetic and Phenotypic Markers of Treatment Complexity and Sustained Use
newsantidepressantsmajor depressive disorder

Decoding Antidepressant Response: Genetic and Phenotypic Markers of Treatment Complexity and Sustained Use

By MedXY|Jan 31, 2026

A large-scale retrospective cohort study identifies specific phenotypic traits and genetic markers, including the SLAMF3/LY9 locus, that predict antidepressant treatment complexity and sustained use, offering a roadmap for precision psychia

Functional Connectivity as a Predictor of Transdiagnostic Treatment Outcomes in Internalizing Psychopathologies: Advances and Clinical Implications
Clinical UpdatesFunctional ConnectivityPrecision Psychiatry

Functional Connectivity as a Predictor of Transdiagnostic Treatment Outcomes in Internalizing Psychopathologies: Advances and Clinical Implications

By MedXY|Oct 27, 2025

Whole-brain functional connectivity patterns predict multidimensional treatment outcomes across internalizing psychopathologies and various therapies, highlighting neural network biomarkers for personalized psychiatric care.

Precision Psychiatry Roadmap: Integrating Biology into Mental Disorder Classification and Treatment
Clinical UpdatesbiomarkersMental Disorders

Precision Psychiatry Roadmap: Integrating Biology into Mental Disorder Classification and Treatment

By MedXY|Oct 5, 2025

Mental disorders currently diagnosed symptomatically can be redefined using biology-informed frameworks integrating biological, behavioral, and environmental data. The Precision Psychiatry Roadmap aims to harmonize global research and clini

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