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Optimizing Geographic Atrophy Clinical Trial Design: The Role of Run-In Phases, Single-Arm Architectures, and Functional Endpoints
Clinical UpdatesGeographic Atrophyophthalmology

Optimizing Geographic Atrophy Clinical Trial Design: The Role of Run-In Phases, Single-Arm Architectures, and Functional Endpoints

By MedXY|May 20, 2026

This review synthesizes evidence on improving geographic atrophy trial efficiency through innovative run-in phases, single-arm designs, and superior functional biomarkers like microperimetry to reduce required sample sizes.

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