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PLCOm2012 风险分层选择优于 NELSON 标准用于德国肺癌检测:HANSE 队列研究结果

在 HANSE 研究中,PLCOm2012(6 年风险 ≥1.58%)选择了更多的肺癌病例,并且筛查所需的样本数量低于 NELSON 标准,支持在 CT 筛查项目中使用风险模型选择,但需注意其普遍性和死亡率终点的局限性。

Nov 26, 2025
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PLCOm2012 Risk-Based Selection Outperforms NELSON Criteria for Lung Cancer Detection in Germany: Findings from the HANSE Cohort

In HANSE, PLCOm2012 (6‑year risk ≥1.58%) selected more lung cancers and yielded a lower number needed to screen than NELSON criteria, supporting risk-model selection for CT screening programs, with caveats on generalisability and mortality

Nov 26, 2025

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