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A Simple Five-Variable Index Helps Identify Excess Alcohol Use in Steatotic Liver Disease When PEth Testing Is Not Readily Available
GastroenterologyALDMetALD

A Simple Five-Variable Index Helps Identify Excess Alcohol Use in Steatotic Liver Disease When PEth Testing Is Not Readily Available

By MedXY|May 7, 2026

A new five-component biomarker panel, MAPI, showed consistent AUROC performance of about 0.75 for detecting MetALD-ALD and may help triage confirmatory PEth testing in steatotic liver disease.

Phosphatidylethanol Reveals Substantial Underestimation of Alcohol Intake in Patients at Risk of Steatotic Liver Disease
GastroenterologyMASLDphosphatidylethanol
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Phosphatidylethanol Reveals Substantial Underestimation of Alcohol Intake in Patients at Risk of Steatotic Liver Disease

By MedXY|Nov 9, 2025

A large prospective cohort shows phosphatidylethanol (PEth) correlates with self-reported alcohol intake but identifies frequent under-reporting; adding PEth to diagnostic pathways could improve subclassification of steatotic liver disease

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