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PGT-A for Severe Male Infertility: Reducing Pregnancy Loss Without Boosting Live Birth Rates
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PGT-A for Severe Male Infertility: Reducing Pregnancy Loss Without Boosting Live Birth Rates

By MedXY|Jan 22, 2026

A multicentre RCT published in the BMJ demonstrates that while PGT-A does not increase cumulative live birth rates for couples with severe male infertility, it significantly reduces the risk of pregnancy loss, providing a nuanced framework

Rethinking Mosaicism: Why Reporting Putative Mosaic Embryos Fails to Improve IVF Outcomes
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Rethinking Mosaicism: Why Reporting Putative Mosaic Embryos Fails to Improve IVF Outcomes

By MedXY|Dec 24, 2025

A large, double-blinded study reveals that reporting embryo mosaicism (ICN) during PGT-A provides no meaningful clinical predictive value for live birth rates, suggesting that current classification systems may unnecessarily limit embryo se

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