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This study examines how participant-reported outcomes relate to residual beta cell function and metabolic control in youth newly diagnosed with type 1 diabetes, highlighting modest associations with glucose management but weaker links to be
The adaptive Sinonasal Outcome Test (SNOT) demonstrates strong validity, reliability, and responsiveness in assessing symptoms and treatment outcomes in chronic rhinosinusitis, correlating well with objective CT imaging and overall health m
Recent research demonstrates that machine learning algorithms can accurately predict patient-reported outcomes one year after breast reconstruction, potentially enhancing shared decision-making and individualized care planning.
A novel adaptive Sino-Nasal Outcome Test (SNOT) yields improved correlation with computed tomography findings in chronic rhinosinusitis, enhancing clinical assessment and differentiation from allergic rhinitis.
This study found that patient-reported speech/voice and related head-and-neck symptoms can help predict hypoglossal neuropathy risk after oropharyngeal cancer treatment, supporting earlier surveillance with the MDASI-HN-NERVE score.
A 2026 review shows that many patients with acromegaly remain symptomatic and functionally impaired despite biochemical control, underscoring the need for routine patient-reported outcomes and lower-burden, multidisciplinary care.
A single-center validation study suggests the CTCL-PRO-20 may provide a reliable, disease-specific measure of quality of life in patients with cutaneous T-cell lymphoma.
A prospective study identifies exhaustion, head and neck discomfort, and body image concerns as independent predictors of poor emotional functioning in differentiated thyroid carcinoma patients. These findings highlight actionable targets f
A prospective cohort study reveals that patients with low-risk papillary thyroid cancer experience similar quality of life outcomes at three years whether they choose active surveillance or immediate surgery, though those who crossover to s
This review details the development and psychometric validation of the TCQOLI, a novel thyroid-cancer-specific utility measure designed to provide precise preference-based health state valuations for clinical research and policy-making.
Explore how standardized health questionnaires empower children and parents to share their priorities in medical settings, leading to more personalized and effective treatment plans.
A multinational randomized trial demonstrates that providing oncologists with patient-reported outcome data significantly improves the inter-rater reliability of CTCAE ratings for symptomatic adverse events, addressing a long-standing gap i
A multisite study reveals that financial toxicity significantly reduces life satisfaction in cancer patients. However, hopefulness and social support act as critical mediators, suggesting that integrating psychosocial resilience training wi
A cross-sectional analysis of the HOPE Consortium Trial reveals that chronic pain in hemodialysis patients is widespread, frequently musculoskeletal and neuropathic, and strongly associated with psychological and sociodemographic factors ra
A multicenter study reveals significant discordance between clinician and patient assessments of skin cGVHD. While both correlate with survival, patient-reported outcomes are uniquely predictive of mortality in sclerotic disease, highlighti
A large-scale pooled analysis of 17 SWOG trials demonstrates that baseline patient-reported fatigue significantly increases the risk of severe, life-threatening, and fatal toxic effects from systemic cancer therapy, highlighting its role as
A comprehensive meta-analysis demonstrates that patients with papillary thyroid microcarcinoma managed via active surveillance experience significantly better health-related quality of life and fewer treatment-related symptoms than those un
A cohort study validates PROMIS measures for anxiety, depression, and social impact in chronic skin diseases, demonstrating that these standardized tools are reliable for tracking physical and social outcomes in clinical dermatology setting
The E2C2 trial demonstrates that integrating electronic health record (EHR)-facilitated collaborative care with symptom surveillance significantly reduces the burden of anxiety, depression, and fatigue in oncology patients compared to surve
A 12-month US prospective observational study found brivaracetam retention at 12 months of 57% (intent-to-treat) and 72% among those with known treatment status, early improvement in seizure-related disability and PROMIS domains, and a safe
