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Prophylactic Acetaminophen Fails to Improve Intact Survival in Preterm Infants: Lessons from the TREOCAPA Trial

By MedXY|Feb 20, 2026

The TREOCAPA randomized clinical trial demonstrates that while prophylactic intravenous acetaminophen effectively promotes patent ductus arteriosus closure in extremely preterm infants, it does not significantly increase survival without se

Cardiologyexpectant managementpatent ductus arteriosus

Expectant Management Improves Early Survival Without Increasing BPD: Results from the PDA Randomized Clinical Trial

By MedXY|Dec 12, 2025

In extremely preterm infants with a protocol-defined PDA, expectant management yielded similar rates of death or BPD at 36 weeks’ postmenstrual age but significantly higher survival compared with active pharmacologic closure.