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organ dysfunction

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Critical Care

SOFA-2 Recalibrated: Global Development and Validation of an Updated Organ Dysfunction Score in >3.3 Million ICU Admissions

SOFA-2 updates the 30-year-old SOFA score using data from >3.3 million ICU admissions across diverse settings. The revised tool modestly improves ICU mortality discrimination (AUROC 0.79 vs 0.77) and incorporates contemporary organ suppo

Nov 8, 2025
Anesthesiology

Postoperative Vasopressor Use After Noncardiac Surgery: Patterns, Outcomes, and Clinical Implications from a Global Observational Study

An international study reveals that postoperative vasopressor infusions after noncardiac surgery vary widely across hospitals and are linked to higher mortality and complications, highlighting the need for optimized management strategies.

Oct 27, 2025

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