Tag
This study develops and compares predictive models incorporating claims and patient-reported data to forecast time to first opioid use disorder (OUD) or overdose (OD) among older adults with chronic pain on opioids, identifying key risk fac
A randomized clinical trial of the Relay peer-navigator intervention in New York City found no significant reduction in opioid-related adverse events compared to standard care, despite high patient satisfaction and the intervention’s
Novel benzodiazepine coexposure in opioid overdoses significantly increases the risk of mechanical ventilation and naloxone nonresponse, highlighting a critical challenge in emergency care management.
Overdose deaths from synthetic opioids alone in U.S. youth aged 15–24 surged 168% between 2018 and 2022, now representing one-third of all youth OD fatalities. Clinical vigilance, harm reduction, and targeted prevention are urgently needed.
