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Fast, Broad Oseltamivir Use in Nursing Home Flu Outbreaks May Cut Hospitalizations
Infectious Diseaseschemoprophylaxisinfluenza

Fast, Broad Oseltamivir Use in Nursing Home Flu Outbreaks May Cut Hospitalizations

By MedXY|Jun 15, 2026

In a real-world target trial emulation, starting oseltamivir prophylaxis within 2 days for at least 70% of eligible nursing home residents was linked to fewer hospitalizations, but not lower short-term mortality.

Stepping Down Antihypertensives in Frail Nursing-Home Residents Did Not Reduce Mortality: Results from the RETREAT-FRAIL Trial
CardiologyFrailtynursing home

Stepping Down Antihypertensives in Frail Nursing-Home Residents Did Not Reduce Mortality: Results from the RETREAT-FRAIL Trial

By MedXY|Dec 6, 2025

In the RETREAT-FRAIL randomized trial of nursing-home residents ≥80 years with systolic BP <130 mm Hg, a protocolized step-down of antihypertensive drugs reduced medication burden and raised systolic BP modestly but did not change all-ca

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