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Italian data suggest prolonged warm ischemic times in donation after circulatory death do not compromise kidney and liver transplant outcomes when combined with advanced perfusion techniques, challenging traditional strict cutoffs.
This study compares normothermic machine perfusion and normothermic regional perfusion in DCD liver transplants, demonstrating both advanced methods approach brain death graft survival and improve outcomes over static cold storage.
Sequential use of normothermic regional perfusion and hypothermic machine perfusion in kidney transplants from DCD donors reduces delayed graft function, highlighting enhanced organ preservation strategies.
Normothermic regional perfusion (NRP) offers a promising approach to reduce ischemic injury in pancreas and islet transplantation using donation after circulatory death (DCD) donors, improving graft quality and expanding donor availability.
A comprehensive national study shows both normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) significantly improve graft survival in DCD liver transplantation, supporting their adoption as complementary standards
In a nationwide U.S. analysis of 21,010 adult DCD kidney transplants, normothermic regional perfusion lowered delayed graft function, shortened hospital stay, and improved graft and patient survival, with the greatest benefit in higher-risk
