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Redefining Post-Cardiac Arrest Care: Two-Year TTM2 Data Confirm No Long-Term Advantage for Targeted Hypothermia
Cardiologycardiac arrestNeurocognition

Redefining Post-Cardiac Arrest Care: Two-Year TTM2 Data Confirm No Long-Term Advantage for Targeted Hypothermia

By MedXY|Feb 20, 2026

This 2-year follow-up of the TTM2 trial demonstrates that targeted hypothermia at 33°C provides no long-term benefit for functional or cognitive recovery compared to targeted normothermia. The findings emphasize the importance of early feve

Routine Cerebral Embolic Protection Fails to Mitigate Stroke or Cognitive Decline in TAVI: Results from the BHF PROTECT-TAVI Trial
Cardiologycerebral embolic protectionNeurocognition
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Routine Cerebral Embolic Protection Fails to Mitigate Stroke or Cognitive Decline in TAVI: Results from the BHF PROTECT-TAVI Trial

By MedXY|Jan 18, 2026

The landmark BHF PROTECT-TAVI trial reveals that cerebral embolic protection (CEP) does not reduce periprocedural stroke or cognitive impairment following TAVI. This large-scale study challenges the routine use of embolic filters, suggestin

Processing Speed as a Core Endophenotype: New Evidence from a 115-Study Meta-Analysis in Schizophrenia
newsmeta-analysisNeurocognition

Processing Speed as a Core Endophenotype: New Evidence from a 115-Study Meta-Analysis in Schizophrenia

By MedXY|Dec 23, 2025

A comprehensive meta-analysis involving over 10,000 patients reveals that processing speed impairment is a profound and central deficit in schizophrenia, showing an effect size of -1.52 and playing a critical role in overall cognitive dysfu

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