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Metrnl reduces platelet activation and thrombus formation by promoting CD36 degradation, offering a promising therapeutic strategy for thrombotic diseases including acute myocardial infarction without increasing bleeding risk.
A large multicohort and experimental study suggests the cTnI/cTnT ratio is biologically informative, separates acute from chronic myocardial injury, and modestly improves type 1 versus type 2 MI discrimination.
A prospective ARIC cohort study reveals that diabetes fundamentally modifies the relationship between the triglyceride-glucose (TyG) index and subclinical myocardial injury, shifting the risk profile from an L-shaped to a J-shaped associati
A VISION cohort analysis found myocardial injury after major head and neck surgery (MINS) in 11.9% overall and 23.8% of patients ≥75, strongly associated with 30‑day mortality and longer hospital stay; most events were clinically silent wit
A large randomized trial shows that ivabradine, despite effectively lowering heart rate during surgery, does not reduce myocardial injury after noncardiac surgery, highlighting the complexity of perioperative cardiac risk management.
Post-PCI myocardial injury defined by elevated CKMB is common and linked to increased long-term mortality, with more complex coronary anatomy predicting the injury occurrence.
