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myelodysplastic neoplasms

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Hematology-Oncology

Decoding Bone Marrow Architecture: A New Biomarker for Disease Activity and Treatment Response in Myelodysplastic Neoplasms

Spatial remodeling of bone marrow in myelodysplastic neoplasms (MDS) reveals distinctive tissue-state signatures that better capture disease activity and predict therapeutic response beyond traditional blast counts.

Aug 17, 2026Sign in to read
Hematology-Oncology

Unraveling the FOLR2-IRF2BP2 Axis: How Excess Folic Acid Impairs Erythropoiesis in Myelodysplastic Neoplasms

Excess folic acid promotes erythropoiesis impairment in myelodysplastic neoplasms via the FOLR2-IRF2BP2 axis, revealing potential therapeutic targets involving dietary folic acid restriction and pathway inhibition.

Aug 11, 2026
Hematology-Oncology

Frontline Allogeneic Transplantation Outperforms Pretransplant IPSS-M Downstaging in Myelodysplastic Neoplasms

In adults with myelodysplastic neoplasms undergoing allogeneic transplantation, pretransplant cytoreduction modestly improved IPSS-M in some patients but did not improve post-transplant survival and was associated with higher non-relapse mo

May 21, 2026Sign in to read

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