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mitochondrial metabolism

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Gastroenterology

MTFP1 and Metabolic Reprogramming: Unlocking New Targets in Pancreatic Cancer Liver Metastasis

MTFP1 promotes pancreatic ductal adenocarcinoma liver metastasis by enhancing mitochondrial oxidative phosphorylation via the ROS/PI3K/AKT/c-MYC/SLC1A5 axis, revealing a promising therapeutic target to reverse tumor immune suppression and r

Oct 14, 2026Sign in to read
Hematology-Oncology

Unveiling a Novel Fusion circRNA Regulating Mitochondrial Metabolism in t(4;11) B-cell Acute Lymphoblastic Leukemia

A newly identified KMT2A::AFF1-derived fusion circular RNA (AK_7_3) modulates mitochondrial metabolism and apoptosis in t(4;11) B-ALL, revealing potential therapeutic targets for this high-risk leukemia subtype.

Aug 24, 2026

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