Hematology-Oncologyapoptosismitochondrial metabolism
Unveiling a Novel Fusion circRNA Regulating Mitochondrial Metabolism in t(4;11) B-cell Acute Lymphoblastic Leukemia
By MedXY|Aug 25, 2026
A newly identified KMT2A::AFF1-derived fusion circular RNA (AK_7_3) modulates mitochondrial metabolism and apoptosis in t(4;11) B-ALL, revealing potential therapeutic targets for this high-risk leukemia subtype.