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Timing of Initiation of Methadone Take-Home Dosing: Evidence Synthesis and Clinical Implications for Opioid Use Disorder Management

Early initiation of methadone take-home dosing (5-24 weeks post-induction) reduces mortality and treatment discontinuation, surpassing benefits seen with no take-home dosing. Flexible dosing policies improve retention without increasing ove

Sep 16, 2026Sign in to read
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The 400 Percent Transit Penalty: How Travel Barriers Systemically Restrict Methadone Access

A geospatial analysis in Connecticut reveals that patients relying on public transit face travel times nearly four times longer than those with cars, with over 50% of areas lacking viable transit to methadone clinics, highlighting an urgent

Feb 6, 2026
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Treatment Retention in Opioid Use Disorder During Pregnancy: Buprenorphine vs Methadone Discontinuation Patterns

This nationwide cohort study reveals higher discontinuation rates of buprenorphine than methadone during pregnancy and up to one year postpartum, highlighting significant challenges in treatment retention for opioid use disorder in pregnant

Oct 30, 2025

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