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MedXY AI/MedXY News/Tag: metastatic breast cancer
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Electronic Patient-Reported Outcome Monitoring With Alert-Based Interventions in Metastatic Breast Cancer: A Review of Evidence and Clinical Implications
Clinical Updatesdigital healthpatient-reported outcomes

Electronic Patient-Reported Outcome Monitoring With Alert-Based Interventions in Metastatic Breast Cancer: A Review of Evidence and Clinical Implications

By MedXY|Aug 7, 2026

This review synthesizes clinical trial evidence supporting digital patient-reported outcome monitoring with alert-based interventions to reduce fatigue and improve physical functioning in metastatic breast cancer.

Palbociclib Extends Progression-Free Survival in HR+/HER2+ Metastatic Breast Cancer: Insights from the PATINA Trial
newsCDK4/6 inhibitors
metastatic breast cancer

Palbociclib Extends Progression-Free Survival in HR+/HER2+ Metastatic Breast Cancer: Insights from the PATINA Trial

By MedXY|Feb 2, 2026

The Phase 3 PATINA trial demonstrates that adding palbociclib to maintenance anti-HER2 and endocrine therapy significantly improves progression-free survival in HR+/HER2+ metastatic breast cancer patients, increasing the median duration fro

Synergistic Potential and Hematologic Hurdles: Sapacitabine and Olaparib in BRCA1/2-Mutated Metastatic Breast Cancer
newsclinical trialsmetastatic breast cancer

Synergistic Potential and Hematologic Hurdles: Sapacitabine and Olaparib in BRCA1/2-Mutated Metastatic Breast Cancer

By MedXY|Jan 12, 2026

A Phase Ib study of sapacitabine and olaparib in gBRCA-mutated metastatic breast cancer showed a 50% objective response rate and 9.7-month median PFS. While significant hematological toxicities limited dose escalation, the combination demon

Elacestrant Reinforces Its Role in the Real-World Management of ESR1-Mutated Metastatic Breast Cancer
newsendocrine therapyESR1 mutation

Elacestrant Reinforces Its Role in the Real-World Management of ESR1-Mutated Metastatic Breast Cancer

By MedXY|Jan 8, 2026

This real-world study demonstrates that elacestrant provides a durable benefit for patients with ER+/HER2- ESR1-mutated metastatic breast cancer, maintaining efficacy across various treatment lines and in patients with visceral metastases o

Breast Surgery in Metastatic Breast Cancer: Local Control Without Survival Benefit
General Surgerymetastatic breast cancerphẫu thuật vú

Breast Surgery in Metastatic Breast Cancer: Local Control Without Survival Benefit

By MedXY|Dec 16, 2025

Randomised trials show breast surgery improves local disease control but not overall survival in de novo metastatic breast cancer.

Trastuzumab Deruxtecan Plus Pertuzumab: A Promising First-Line Therapy for HER2-Positive Metastatic Breast Cancer
newsHER2-positive breast cancermetastatic breast cancer

Trastuzumab Deruxtecan Plus Pertuzumab: A Promising First-Line Therapy for HER2-Positive Metastatic Breast Cancer

By MedXY|Oct 31, 2025

Trastuzumab deruxtecan combined with pertuzumab significantly improves progression-free survival over standard therapy in first-line HER2-positive metastatic breast cancer, offering enhanced response duration with manageable safety.

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