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Circulating Tumor DNA Outperforms Merkel Cell Polyomavirus Antibodies for Monitoring Recurrence in Merkel Cell Carcinoma
Dermatologycancer surveillancectDNA

Circulating Tumor DNA Outperforms Merkel Cell Polyomavirus Antibodies for Monitoring Recurrence in Merkel Cell Carcinoma

By MedXY|Jul 14, 2026

A multicenter cohort study demonstrates that circulating tumor DNA (ctDNA) is more accurate than Merkel cell polyomavirus (MCPyV) antibody testing in detecting recurrence of Merkel cell carcinoma, improving patient surveillance and risk str

Sentinel Lymph Node Biopsy in Head and Neck Merkel Cell Carcinoma: Why High False-Negative Rates Demand Clinical Vigilance
newshead and neck oncologyMerkel Cell Carcinoma

Sentinel Lymph Node Biopsy in Head and Neck Merkel Cell Carcinoma: Why High False-Negative Rates Demand Clinical Vigilance

By MedXY|Mar 18, 2026

A comprehensive cohort study reveals that sentinel lymph node biopsy (SLNB) in head and neck Merkel cell carcinoma has a sensitivity of only 52.6% and a high failure rate. The findings suggest that clinicians must reconsider management stra

The Precision Gap: Evaluating Sentinel Lymph Node Biopsy in Head and Neck Merkel Cell Carcinoma
newshead and neck cancerMerkel Cell Carcinoma

The Precision Gap: Evaluating Sentinel Lymph Node Biopsy in Head and Neck Merkel Cell Carcinoma

By MedXY|Jan 30, 2026

This article examines the clinical accuracy of Sentinel Lymph Node Biopsy for head and neck Merkel cell carcinoma, highlighting a significant false-negative rate and identifying risk factors that necessitate more personalized treatment stra

Neoadjuvant Lenvatinib Plus Pembrolizumab Achieves Robust Pathological Complete Response in Resectable Merkel Cell Carcinoma
Dermatologyimmunotherapylenvatinib

Neoadjuvant Lenvatinib Plus Pembrolizumab Achieves Robust Pathological Complete Response in Resectable Merkel Cell Carcinoma

By MedXY|Jan 19, 2026

A Phase II trial demonstrates that combining lenvatinib with pembrolizumab prior to surgery in Merkel cell carcinoma results in a 57.7% pathological complete response rate, suggesting a highly effective new strategy for managing resectable

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