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Memantine for Premature Atrial Contractions: A Phase 2 Randomized Clinical Trial
Cardiologyatrial fibrillationCardiac Glutamatergic System

Memantine for Premature Atrial Contractions: A Phase 2 Randomized Clinical Trial

By MedXY|Mar 20, 2026

This phase 2 trial demonstrates that memantine, an NMDA receptor antagonist, significantly reduces premature atrial contractions (PACs) and nonsustained atrial tachycardia burden, suggesting the cardiac glutamatergic system as a novel thera

Memantine Shows Promise for Improving Social Impairment in Youths with Autism Spectrum Disorder
Clinical Updatesautism spectrum disorderMemantine

Memantine Shows Promise for Improving Social Impairment in Youths with Autism Spectrum Disorder

By MedXY|Oct 6, 2025

A 12-week randomized clinical trial demonstrates memantine’s efficacy and safety in improving social impairments in youths with ASD, with elevated pgACC glutamate levels serving as a predictive biomarker for treatment response.

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