Memantine

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Memantine for Premature Atrial Contractions: A Phase 2 Randomized Clinical Trial

This phase 2 trial demonstrates that memantine, an NMDA receptor antagonist, significantly reduces premature atrial contractions (PACs) and nonsustained atrial tachycardia burden, suggesting the cardiac glutamatergic system as a novel thera

Mar 20, 2026

Clinical Updates

Memantine Shows Promise for Improving Social Impairment in Youths with Autism Spectrum Disorder

A 12-week randomized clinical trial demonstrates memantine’s efficacy and safety in improving social impairments in youths with ASD, with elevated pgACC glutamate levels serving as a predictive biomarker for treatment response.

Oct 1, 2025